Purity >98% by HPLC. MTS reagent is a tetrazolium inner salt useful for determining the number of viable cells in proliferation or chemosensitivity assays. MTS is bioreduced by cells into a colored formazan product that is soluble in tissue culture medium. This conversion is thought to be carried out by NAD(P)H-dependent dehydrogenase enzymes in metabolically active cells.
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Other Names
Owen's reagent, MTS Reagent powder, 3-(4,5-Dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt