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Description
EPHA2 Polyclonal Antibody, Alexa Fluor? 647 Conjugated. ? Target Background: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation
Immunogen
KLH conjugated synthetic peptide derived from human EPHA2. Immunogen Range: 440-490/976