Purity ~90% (SDS-PAGE). Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Source: Recombinant protein corresponding to aa24-150 from human C-C Motif Chemokine 25, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~41.2kD AA