Purity ~90% (SDS-PAGE). Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Source: Recombinant protein corresponding to aa24-99 from human CCL2, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~35.7kD AA
Size
10ug, 50ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
HC11 Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF Monocyte chemotactic protein 1, MCP-1 Monocyte secretory protein, JESmall-inducible cytokine A2