Purity ~90% (SDS-PAGE). Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induced intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and was inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5. Source: Recombinant protein corresponding to aa20-93 from human CCL14, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~24.7kD AA