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Description
ASK1 (Thr845) Polyclonal Antibody, Biotin Conjugated. ? Target Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host def
Immunogen
KLH conjugated synthetic phosphopeptide derived from mouse ASK1 around the phosphorylation site of Thr845. Immunogen Range: 825-875/1380