Purity ~85% (SDS-PAGE). NSL1 is a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome- associated structures that attach to microtubules and mediate chromosome movements during cell division. The protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. Source: Recombinant protein corresponding to human NSL1, fused to His-tag at N-terminal expressed in E.coli. Molecular Weight: ~34.6kD (304aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAGSPEL VVLDPPWDKE LAAGTESQAL VSATPREDFR VRCTSKRAVT EMLQLCGRFV QKLGDALPEE IREPALRDAQ WTFESAVQEN ISINGQAWQE ASDNCFMDSD IKVLEDQFDE IIVDIATKRK QYPRKILECV IKTIKAKQEI LKQYHPVVHP LDLKYDPDPA PHMENLKCRG ETVAKEISEA MKSLPALIEQ GEGFSQVLRM QPVIHLQ
Size
100ug
Concentration
n/a
Applications
n/a
Other Names
NSL1, Recombinant, Human, aa1-281, His-Tag (Kinetochore-associated Protein NSL1 Homolog, MIND Kinetochore Complex Component, Homolog (S. cerevisiae), C1orf48, DC8, MIS14)