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Description
Ki-M9R detects a cytoplasmic antigen in accessory B-cells which are involved in antigen trapping reactions. The antigen is only expressed in sinus lining cells of lymph nodes, in follicular dendritic cells of germinal centres, and in metallophilic cells of the spleen. Thus it seems that the antigen is associated with antigen processing cells that migrate to germinal centres to develop into follicular dendritic cells. Application: IHC (f)