Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. FCER2, also known as low affinity immunoglobulin epsilon Fc receptor isoform a, is a member of subgroup II of the C-type (Ca++-dependent) lectin superfamily. It is a low affinity receptor for B cell specific antigen and IgE. It plays an essential role in the growth and differentiation of B cells, and in the regulation of IgE production. This protein also exists in a soluble secretion form and functions as a powerful cleavage-promoting growth factor. Increased levels of soluble CD23 / FCER2 lead to the recruitment of unaffected B cells in the presentation of antigen peptides to allergen-specific B cells. Recombinant human FCER2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size
50ug, 10ug,
Concentration
n/a
Applications
SDS-PAGE
Other Names
Low affinity immunoglobulin epsilon Fc receptor isoform a, FECR2, BLAST-2, CD23, CD23A, CLEC4J, FCE2, IGEBF