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| Antigenic Specificity | SUMO1 Activating Enzyme Subunit 1 (SAE1) (Internal Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, cow, mouse, rat, dog |
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| Isotype | n/a |
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| Format | purified |
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| Size | 25 μL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),ELISA |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SUMO E1 activating enzyme (also called Ubiquitin-like 1 activating enzyme E1A, UBLE1A, AOS1, SAE1, and SUA1) with SAE2 (also known as UBA2) forms a heterodimeric (SAE1/SAE2) enzyme that activates the ubiquitin-like SUMO proteins (SUMO stands for Small Ubiquitin-like MOdifier.) The SAE1 (SUMO Activating Enzyme 1) subunit resembles the N-terminal half of yeast UBA1; the SAE2 (also called Uba2) subunit corresponds to the C-terminal part of yeast UBA1 and contains the active site cysteine. In the SUMO activation step, SAE1/SAE2 uses ATP to adenylate the C-terminal glycine of SUMO-1 (the first of the three different mammalian SUMO proteins) then forms a high-energy thioester bond between the C-terminal glycine and the active site cysteine in SAE2 (Uba2). In the conjugation step, the SUMO moiety is transferred from SAE1/SAE2 to the active site cysteine (Cys 93) of the SUMO conjugating enzyme (SUMO E2, Ubc9) forming a SUMO-E2 thioester complex.Synonyms: SUMO E1 activating enzyme Ubiquitin-like 1 activating enzyme E1A UBLE1A AOS1 SAE1 SUA1 |
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| Immunogen | This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human SUMO Activating Enzyme E1 protein.Immunogen Type: Peptide |
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| Other Names | AOS1|CDGAP|HSPC140|SUA1|UBLE1A|2400010M20Rik|2610044L12Rik|AL033372|AW743391|D7Ertd177e|Sua1|Uble1a|Aos1p|Sua1p|aos |
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| Gene, Accession # | n/a |
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| Catalog # | ABIN964925 |
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| Price | |
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| Order / More Info | SUMO1 Activating Enzyme Subunit 1 (SAE1) (Internal Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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