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Description
Monoclonal antibody EDU-1 recognizes the HLA DR antigen, an HLA class II antigen with homology to murine H-2E. HLA-DR is an αβ heterodimer. The N-terminal domain of the mature protein forms an alpha-helix that constitutes the exposed part of the binding groove, the C-terminal cytoplasmic region interacts with the other chain forming a beta-sheet under the binding groove spanning to the cell membrane