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Description
Phospho-Smad3 (Thr179) Antibody detects endogenous levels of Smad3 only when phosphorylated at Threonine 179. Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.
Immunogen
n/a
Other Names
JV15-2; MAD-3; MADH3; Mad3; Mothers against DPP homolog 3; Mothers against decapentaplegic homolog 3; SMAD 3; MAD homolog 3; hMAD-3; SMAD family member 3; Smad3; hSMAD3