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Description
Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family D member 3(ABCD3) detection. Tested with WB, IHC-P in Human;Mouse;Rat. No cross reactivity with other proteins. ATP-binding cassette sub-family D member 3 is a protein that in humans is encoded by the ABCD3 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. The gene was assigned to human chromosome 1p21-p22 by in situ hybridization. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human PMP70(646-659aa EFKQITEDTVEFGS), different from the related mouse and rat sequences by one amino acid.
Other Names
ATP-binding cassette sub-family D member 3;70 kDa peroxisomal membrane protein;PMP70;ABCD3;PMP70, PXMP1;