A PEGylated derivative of DSPE; has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents; has been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications; can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles