Purity: > 80% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea. BRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. Recombinant human BRMS1 protein, fused to T7-tag at N-terminus, was expressed in E.coli .
Size
100ug, 20ug, 4ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Breast cancer metastasis suppressor 1 isoform 1, Breast cancer metastasis suppressor 1, DKFZp564A063