ASIC blocker (IC50 values are 202, ~320, ~320 and 864 nM for ASIC1b, ASIC1a, ASIC3 and ASIC2a, respectively). Exhibits no activity in ENaC channels expressed in oocytes. Accelerates desensitization of ASIC currents in hippocampal neurons. Inhibits mesotrypsin (Ki = 3.6?0.3 μM). Displays in vitro and in vivo anti-inflammatory effects in mice. Antihyperalgesic. Purity 98%. MW (observed): 515.52