Purity ~90% (SDS-PAGE). Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. Source: Recombinant protein corresponding to aa1-277 from human ZWINT, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~58.2kD AA