BAFF, Recombinant, Human (B cell Activating Factor belonging to TNF Family, BLyS, TALL-1, THANK)
Description
Purity ≥95% by SDS-PAGE and HPLC. Endotoxin:≤0.1ng/ug (1EU/ug). Human BAFF (for B cell activating factor belonging to the TNF family) is a newly discovered novel ligand of the TNF family. BAFF plays an important role as costimulator of B cell proliferation and function. Recombinant Human BAFF is a soluble 17kD protein containing 153 amino acid residues, comprising the TNF-like extra-celluar domain of BAFF. Biological Activity: Assay#1: Determined by the dose-dependent stimulation of IL-8 production by Human PBMC (Peripheral Blood Mononuclear Cells). The ED50 for this effect is 5-10ng/ml. Please Note: Results may vary with PBMC donors. Assay#2: Determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5-2.0ug/ml.