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Description
Crry Polyclonal Antibody, Biotin Conjugated. ? Target Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
Immunogen
KLH conjugated synthetic peptide derived from human Crry. Immunogen Range: 105-135/559
Other Names
Mcp; Crry; mCRY; Complement component receptor 1-like protein; Complement regulatory protein Crry; Protein p65; Cr1l; Cry