Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT. Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, also known as COA4, is the last enzyme of the mitochondrial respiratory chain, is a very complicated process and requires the assistance of a large number of accessory factors. It is essential for oxidative phosphorylation and comprises multiple complexes, including cytochrome c oxidase, assembled in macromolecular supercomplexes. Defects in COX4 assembly alter cellular respiration and produce severe human encephalomyopathies. Recombinant human COA4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size
250ug, 50ug, 10ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Cytochrome c oxidase assembly factor 4 homolog mitochondrial, Cytochrome c oxidase assembly factor 4 homolog, mitochondrial, CHCHD8, CMC3, E2IG2