N-Terminal EF-Hand Calcium Binding Protein 1 (NECAB1)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
mouse, rat, human
Isotype
n/a
Format
affinity purified
Size
100 μg
Concentration
n/a
Applications
Western Blotting (WB),Immunohistochemistry (IHC)
Reviews / Ratings
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Description
HOP, also known as stress-induced phospho protein 1 (STIP), is a co-chaperone to the major heat shock proteins, Hsp70 and Hsp90, and appears in early receptor complexes. Through mutual binding to both Hsp70 and Hsp90, Hop functions as an adaptor that can integrate Hsp70 and Hsp90 interactions. HOP is an abundant and highly conserved protein which is composed of three tetratricopeptide repeat (TPR) domains (TPR1, TPR2a and TPR2b) and two DP repeat domains (DP1 and DP2), whose function has not been fully resolved.Synonyms: STIP1, HOP, IEF-SSP-3521, P60, STI1, STI1L