Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000
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Description
CHN1 Polyclonal Antibody. This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene.