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| Antigenic Specificity | TRP12 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor? 488 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TRP12 Polyclonal Antibody, Alexa Fluor? 488 Conjugated. ? Target Background: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and |
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| Immunogen | KLH conjugated synthetic peptide derived from human TRPV4. Immunogen Range: 310-360/871 |
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| Other Names | SMAL; VRL2; BCYM3; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1; Transient receptor potential cation channel subfamily V member 4; TrpV4; Osm-9-like TRP channel 4; Transient receptor potential protein 12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC |
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| Gene, Accession # | Gene ID: 59341, SwissProt: Q9HBA0 |
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| Catalog # | bs-6425R-A488 |
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| Price | |
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| Order / More Info | TRP12 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Ghoneum, M.H., et al. (2018) Nanomaterials. PubMed: 30274279 |
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