If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
IRF7 (Ser471 + Ser472) Antibody, Cy7 Conjugated. ? Target Background: Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88
Immunogen
KLH conjugated synthetic phosphopeptide derived from human IRF7 around the phosphorylation site of Ser471/472. Immunogen Range: 450-490/503