Click-activated Thalidomide (Cat.No. 0652); can be used as a precursor to PROTACs that hijack cereblon as the E3 ubiquitin ligase component. Supplied with an alkyne functional handle at a position known not to significantly affect binding to cereblon, for ready click conjugation to a linker/target protein ligand. Require a different derivative? Get in touch. Purity 95%. MW (observed): 312.28