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Description
The protein encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout. This antibody is supplied as crude ascites. This HPRT1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from human HPRT1.
Immunogen
Human HPRT1.
Other Names
Hgprt; Hprt1; Hprtphosphoribosyltransferase Human Protein; HPRT; Hypoxanthine-guanine phosphoribosyltransferase