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Description
PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases
Immunogen
Recombinant human PDCD1 (21-167aa) purified from E. coli
Other Names
Programmed cell death 1, CD279, PD1, hPD-1, hPD-l,