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| Antigenic Specificity | Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) |
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| Clone | 2B11 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. |
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| Immunogen | Purified recombinant fragment of human LRP5 expressed in E. coli. |
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| Other Names | Xlrp5|bmnd1|evr1|evr4|hbm|lr3|lrp5-A|lrp7|oppg|ops|opta1|vbch2|LRP5|LRP6|BMND1|EVR1|EVR4|HBM|LR3|LRP7|OPPG|OPS|OPTA1|VBCH2|mKIAA4142 |
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| Gene, Accession # | Gene ID: 4041 |
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| Catalog # | ABIN969535 |
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| Price | |
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| Order / More Info | Low Density Lipoprotein Receptor-Related Protein 5 (LRP5) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 19571442, 20045498 |
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