A peptide hormone; binds to the orphan receptor GPR39 (Kd = 1 nM) and stimulates cAMP production in CHO and HEK293 cells overexpressing human GPR39; suppresses food intake in a time- and dose-dependent manner and reduces body weight gain and gastric emptying in mice (12.5-1,000 nmol/kg); reduces food intake and glucose response without affecting plasma insulin responses in fasted high-fat diet fed mice (0.22 g per animal) ,