A peptide hormone that binds to GHS-R; increases intracellular calcium in CHO cells expressing rat GHS-R (EC50 = 2.5 nM) and induces GH release from primary rat pituitary cells (EC50 = 2.1 nM); reduces glucose-, arginine-, and carbachol-induced insulin release and arginine-induced somatostatin release from perfused rat pancreas (10 nM); increases GH plasma levels in anesthetized rats; increases gastric motility in rats in a dose-dependent manner and increases food intake and body weight (1 μg per animal)
Size
500 μg
Concentration
n/a
Applications
n/a
Other Names
chinese hamster ovary ghrelin-28 Rattus norvegicus GHSR 258338-12-4