Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000
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Description
TNIP3 Polyclonal Antibody. TNIP3 binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. It Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Immunogen
n/a
Other Names
ABIN-3, LIND, A20-binding inhibitor of NF-kappa-B activation 3, ABIN-3 beta, Listeria induced, TNFAIP3-interacting protein 3, TNFAIP3-interacting protein 3 beta, TNIP3 beta, listeria-induced gene protein