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Description
Mouse Anti-EDA2R Recombinant Antibody (2L23). Provided herein is a Mouse monoclonal antibody against Human EDA2R. The antibody, clone 2L23, can be used for immunoassay techniques, such as Neut, WB. EDA2R is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. EDA2R binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. EDA2R mediates the activation of the NF-kappa-B and JNK pathways and activation seems to be mediated by binding to TRAF3 and TRAF6.