AKR7A2, 1-359aa, Human, His tag, E. coli (Bioactivity Validated)
Description
Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 20% glycerol . Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to gamma-Hydroxybutyrate in human brain. Recombinant AKR7A2 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
Enzyme activity
Other Names
aldo-keto reductase family 7 member A2, Aflatoxin B1 aldehyde reductase member 2, AFAR, AFAR1, AFB1-AR1, AKR7, aldo-keto reductase family 7, member A2 AFB1 AR1, AFB1AR1, aflatoxin aldehyde reductase, aflatoxin beta1 aldehyde reductase, Aiar, aldo keto reductase family 7, aldo keto reductase family 7, member A2, aldoketoreductase 7.