Purity >95%. N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of Alpha-D-galactosidase. It has also been shown to prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders by inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 μM) without affecting Alpha-glucosidase I and II or Beta-glucocerebrosidase (IC50 s > 1 mM). This compound has been used to sensitize cultured chronic lymphocytic leukemia cells to the chemotherapeutic agents cladribine , chlorambucil , and fludarabine .