Immunocytochemistry: 1 μg/mL, Immunofluorescence: 1 μg/mL, Western Blot: 1-2 μg/mL
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Description
ZO-3 Antibody (24HCLC), ABfinity? Rabbit Oligoclonal. ZO-3 is a member of the membrane associated guanylate kinse (MAGUK) family and are considered tight junction-associated proteins. Tight junctions are complexes of proteins that create intercellular boundaries between the plasma membrane domains of epithelial and endothelial cells. ZO-3 is believed to have both structural and signaling roles, and is characteristically defined by three protein-protein interaction modules: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin at tight junction stands, where they provide a linkage between the
Immunogen
n/a
Other Names
TJP3, TJP-3, tight junction protein 3 zona occludens 3, tight junction protein ZO-3, ZO3, zona occludens protein 3, zonula occludens protein 3, ZO-3