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| Antigenic Specificity | Caspase-9 Ser196 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Alexa Fluor? 555 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Caspase-9 (Ser196) Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9. |
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| Immunogen | KLH conjugated synthetic phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196. Immunogen Range: 180-220/416 |
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| Other Names | Phosphorylated, phospho-MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6; Caspase-9; CASP-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP9 |
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| Gene, Accession # | Gene ID: 842, SwissProt: P55211 |
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| Catalog # | bs-5241R-A555 |
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| Price | |
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| Order / More Info | Caspase-9 Ser196 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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