Recombinant Rat 3-hydroxyacyl-CoA dehydrogenase type-2 (Hsd17b10)
Description
Purity > 90% as determined by SDS-PAGE. MW: 29.1kDa. Full Length of Mature Protein: 2-261aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids