Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH7.4) containing 30% glycerol. Ogg1, also known as N-glycosylase/DNA lyase, is a DNA glycosylase enzyme involved in base excision repair. This protein is the primary enzyme responsible for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen species (ROS). It has a beta lyase activity that nicks DNA 3 to the lesion. Recombinant mouse Ogg1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography