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Description
Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.
Immunogen
Mouse Khdrbs1.
Other Names
Khdrbs1; KH domain-containing; RNA-binding; signal transduction-associated protein 1; GAP-associated tyrosine phosphoprotein p62; Src-associated in mitosis 68 kDa protein; p21 Ras GTPase-activating protein-associated p62; p68