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Description
Rabbit polyclonal to RORA.Nuclear receptor ROR-alpha ORA) is an orphan nuclear receptor that belongs to the nuclear hormone receptor family, NR1 subfamily. RORA binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceeded by a short A-T-rich sequence. RORA regulates a number of genes involved in lipid metabolism, such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma; in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3; in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. RORA is a possible receptor for cholesterol or one of its derivatives.
Immunogen
C-terminal region of mouse RORA
Other Names
RORA,Nuclear receptor RORalpha,Nuclear receptor RZRalpha,Nuclear receptor subfamily 1 group F member 1,Retinoidrelated orphan receptoralpha,Nr1f1,Rzra