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Description
Mouse anti human RORC monoclonal antibody for WB, FC. ROR gamma (Nuclear receptor ROR-gamma), also called RORC and NR1F3, is a member of the NR1 nuclear hormone receptor family. ROR gamma is a DNA binding transcription factor. ROR gamma is 518 amino acids (aa) in length. Deletion in mice implicates ROR gamma as being essential for lymphoid organogenesis and controlling apoptosis during thymopoiesis. Two splice forms differing in the first 24 aa have been found for this gene; isoform 2 deletes aa 1?21 resulting in an alteration of aa 22?24. Over aa 1?121 human ROR gamma shares 97% identity with mouse ROR gamma.