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Description
Mouse Anti-TRMT1 Recombinant Antibody (CBYJT-4865). Provided herein is a Mouse monoclonal antibody, which binds to TRMT1 (TRNA Methyltransferase 1). The antibody can be used for immunoassay techniques, such as WB, IF. TRMT1 is a tRNA-modifying enzyme that acts as a dimethyltransferase, modifying a single guanine residue at position 26 of the tRNA. The encoded enzyme has both mono- and dimethylase activity when exogenously expressed, and uses S-adenosyl methionine as a methyl donor. The C-terminal region of the encoded protein has both a zinc finger motif, and an arginine/proline-rich region. Mutations in TRMT1 have been implicated in autosomal recessive intellectual disorder (ARID).
Immunogen
Full length human recombinant protein of human TRMU (NP_060476) produced in HEK293T cell