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Description
Rabbit polyclonal to HSP90AB1. Heat shock protein HSP 90-beta (HSP90AB1) belongs to the heat shock protein 90 family. HSP90AB1 is a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. HSP90AB1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Furthermore, interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.