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Description
Mouse Anti-BACE1 Recombinant Antibody (CBYY-0117). This product is mouse antibody that recognizes BACE1. The antibody CBYY-0117 can be used for immunoassay techniques such as: ELISA, WB. This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients.
Immunogen
Full-length recombinant corresponding to aa22-502 from BACE1 (AAH65492) with GST tag. MW of the GST tag alone is 26kD