If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Estrogen receptor beta Antibody, Cy3 Conjugated. ? Target Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol
Immunogen
KLH conjugated synthetic peptide derived from human ER-beta. Immunogen Range: 220-270/530
Other Names
Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; ESR2