| Edit |   |
|---|
| Antigenic Specificity | SRY (Sex Determining Region Y)-Box 2 (SOX2) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunocytochemistry (ICC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | SRY (sex determining region Y)-box 2, also known as SOX2, is a transcription factor that is essential to maintain self-renewal of undifferentiated embryonic stem cells. Sox2, Oct-4 and Nanog co-operate in this network, and siRNA knockdown of either Sox2 or Oct-4 results in loss of pluripotency. POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 are the four Yamanaka factors. When combined, these factors are sufficient to reprogram differentiated cells to an embryonic-like state designated iPS (induced pluripotent stem) cells. |
|---|
| Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of SOX2. |
|---|
| Other Names | Qscn6|Qsox|Sox-2|rSOx|ANOP3|MCOPS3|RGD1565646|SRY-box2|Xsox-2|anop3|mcops3|sox-2|lcc|ysb|cb236|wu:fb83g04|wu:fc14d07|zgc:65860|zgc:77389 |
|---|
| Gene, Accession # | Gene ID: 6657 |
|---|
| Catalog # | ABIN871137 |
|---|
| Price | |
|---|
| Order / More Info | SRY (Sex Determining Region Y)-Box 2 (SOX2) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|