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Description
Estrogen Receptor beta (ser105) Antibody. ? Target Background: This gene encodes a member of the family of estrogenreceptors and superfamily of nuclear receptor transcriptionfactors. The gene product contains an N-terminal DNA binding domainand C-terminal ligand binding domain and is localized to thenucleus, cytoplasm, and mitochondria. Upon binding to17beta-estradiol or related ligands, the encoded protein formshomo- or hetero-dimers that interact with specific DNA sequences toactivate transcription. Some isoforms dominantly inhibit theactivity of other es
Immunogen
KLH conjugated synthetic phosphopeptide derived from human ER-beta around the phosphorylation site of ser105 [HL(p-S)PL]