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| Antigenic Specificity | C-C Chemokine Receptor Type 5 (CCR5) (Extracellular Domain) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 40 μg |
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| Concentration | n/a |
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| Applications | ELISA,Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The CC chemokine receptor 5 (CCR5) is a member of the CC chemokine receptor family. It has the characteristic structure of a 7 transmembrane G protein-coupled receptor (GPCR). CCR5 is a receptor for a number of inflammatory CC chemokines including MIP-1-alpha, MIP-1-beta and RANTES. It transduces a signal by increasing the intracellular calcium ion level and may play a role in the control of granulocytic lineage proliferation or differentiation. It also acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates. CCR5 is highly expressed in spleen, thymus, and also in the myeloid cell line THP-1, the promyeloblastic cell line KG-1A and on the CD4+ and CD8+ T-cells. Moreover, recent studies have highlighted the role of CCR5 in a variety of human diseases, ranging from infectious and inflammatory diseases to cancer.Rabbit Anti-CCR5 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide derived from extracellular domain of human CCR5. |
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| Immunogen | KLH-coupled synthetic peptide derived from extracellular domain of human CCR5. |
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| Other Names | AM4-7|CD195|Cmkbr5|Ckr5|CC-CKR-5|CCR-5|CMKBR5|GPCR|CCR5|CCCKR5|CKR-5|CKR5|IDDM22 |
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| Gene, Accession # | Gene ID: 1234 |
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| Catalog # | ABIN1573999 |
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| Price | |
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| Order / More Info | C-C Chemokine Receptor Type 5 (CCR5) (Extracellular Domain) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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