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Description
Mouse Anti-APC Recombinant Antibody (ALi 12-28). This product is a mouse antibody that recognizes APC of human. The antibody ALi 12-28 can be used for immunoassay techniques such as: IF, FC, WB, IHC-Fr. This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. APC activity is corr
Immunogen
N-terminal fragment (aa. 1-433) of human APC (Adenomutons Polyposis Coli gene Chr 5q) fused to maltose binding protein.