A thrombopoietin receptor agonist (EC50 = 0.27 μM) and iron chelator; It increases STAT5 phosphorylation in N2C-Tpo cells at 30 μM and p42/44 MAPK phosphorylation at 10 μM; stimulates megakaryocytopoiesis in human primary bone marrow cells; increases platelet production in chimpanzees at 10 mg/kg per day for five days; binds to iron (III) and mobilizes cellular iron and ferritin in H9C2, Huh7, and RINm5F cells